Serum Gonadotrophin for Injectioninstructions

Common Name

Serum Gonadotrophin for Injection

Trade Name

Kuaiyiyun

English Name

Serum Gonadotrophin for Injection

Chinese Pinyin

Zhusheyong Xuecuxingsu

Main Ingredient

Pregnant Mare Serum Gonadotrophin

Characteristics

This product is white freeze-dried block or powder.

Pharmacological Action

Serum Gonadotrophin belongs to the category of hormone. Pregnant Mare Serum Gonadotrophin (PMSG) is a natural glycoprotein, is composed of two subunits (α subunit and β subunit). It is extracted from the serum of pregnant mares and used as a veterinary drug. It has follicle- stimulating hormone (FSH) and luteinizing hormone (LH) -like effects.

For female dogs/cats:

1.It mainly plays the role of follicle stimulating hormone, promotes the development and maturation of follicles, and causes estrus.

2.It also has a mild luteinizing hormone-like effect, which promotes ovulation of mature follicles and even superovulation.

For male dogs/cats:

1.It mainly plays the role of luteogenesis.

2.It can increase the secretion of androgen and improve sexual excitement.

Pharmacokinetic characteristics after injection of Pregnant Mare Serum Gonadotrophin (PMSG) : Highly glycosylated (N- and O-glycosylation) leads to an extremely long half-life, that's why a single injection of Pregnant Mare Serum Gonadotrophin can support follicular growth throughout the follicular phase (2-5 days, depending on the species).

Pregnant Mare Serum Gonadotrophin (PMSG) is with rapid absorption: After injection, the drug is rapidly absorbed from the injection site, and blood concentration reaches its peak 8-16 hours after injection.

Pregnant Mare Serum Gonadotrophin (PMSG) is with slow elimination: Elimination half-life ranges from 34-150 hours, depending on the species.

Indications

Hormone drug. It is mainly used for female dogs/cats to induce aphrodisiac and stimulate the development of follicles, and is also used for superovulation during embryo transfer. For male dogs/cats, it is used to increase the secretion of androgen and improve sexual excitement.

Dosage and Administration

This product is white freeze-dried block or powder, dilute it just before use. Dogs/cats: 20IU/KG, Subcutaneous injection every day, continuous injection for several days. Before mating, an appropriate amount of Chorionic Gonadotropin (hCG) can be administered. Or follow veterinarian's order.

Adverse Reactions

According to prescribed usage and dosage, no adverse reactions have been observed.

Precautions

1. It should not be used for a long time, so as not to produce antibodies and inhibit pituitary gonadotropin function.

2.This solution product is extremely unstable and not heat-resistant, and should be used up in a short time.

Specification

1000 IU

Package

5* 1000 IU+5 Diluent

Storage

Keep out of light, airtight and store in a cold place

Shelf Life

2 years